Abstract
Background Pulmonary arterial hypertension (PAH) is characterized by RV dysfunction. However, abnormal ventricular interactions also result in abnormalities of systolic and diastolic LV function. Unfortunately, these changes may be subtle and are often overlooked in clinical assessment. In this study, a novel self-gated tissue phase mapping (TPM) sequence was used to evaluate the components of LV motion in patients with PAH. The aim was to better characterize abnormal LV function and to assess its functional significance.
Highlights
Pulmonary arterial hypertension (PAH) is characterized by RV dysfunction
A novel self-gated tissue phase mapping (TPM) sequence was used to evaluate the components of LV motion in patients with PAH
The LVEDV was lower in PAH with preserved ejection fraction compared to normal controls
Summary
Pulmonary arterial hypertension (PAH) is characterized by RV dysfunction. Abnormal ventricular interactions result in abnormalities of systolic and diastolic LV function. These changes may be subtle and are often overlooked in clinical assessment. A novel self-gated tissue phase mapping (TPM) sequence was used to evaluate the components of LV motion in patients with PAH. The aim was to better characterize abnormal LV function and to assess its functional significance
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