Abstract
In rats, when MHC incompatibility prevails, there is a highly significant difference in the ability of cells prepared from bone marrow and from lymph nodes to induce tolerance of donor strain skin when inoculated intravenously into neonatal recipients. For example, whereas in the Lewis to BN strain combination as few as 7×10 6 (Lewis×BN)F 1 bone marrow cells (BMC) * rendered 5/8 (63%) recipients highly tolerant of Lewis skin, i.e., they subsequently accepted Lewis skin grafts for at least 50 days, 60×10 6 (Lewis×BN)F 1 lymph node cells (LNC) failed to render any of 14 recipients highly tolerant of such grafts (1)
Full Text
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call