Abstract
Background Rheumatoid arthritis (RA) is a chronic disease that is characterized by defeat of the musculoskeletal system and is often accompanied by the anemia. Objectives The aim of our study was to determine the effect of anemia on the structural and functional state of the heart in patients with rheumatoid arthritis. Methods The 154 patients with rheumatoid arthritis were included in the study: 37 patients with anemia (1st group) and 117 – without systemic manifestations of rheumatoid arthritis (2nd group). RA activity was estimated by index DAS-28. All patients underwent echocardiography. Results Both groups were comparable in age, sex, ratio of seropositive and seronegative patients. A comparative analysis of both groups revealed that in 1st group DAS-28 was higher than in 2nd group (p Conclusion Thus, regardless of the presence of anemia, the patients with rheumatoid arthritis observed dependence of structural and functional changes in the heart of age: a violation of diastolic function of the left ventricle, an increase of the left ventricular myocardial mass index,. However, in patients with anemia, an increase in the activity of the disease is accompanied by diastolic dysfunction of the right ventricle that requires correction in the tactics of patient management.
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