AB0021 PTPN22 C1858T Variant is a Risk Factor for Systemic Lupus Erythematosus but not for Rheumatoid Arthritis in the Algerian Population

Abstract

BackgroundPTPN22 is a protein phosphatase regulating negatively T-cell activation and participates in BCR signaling pathways. C1858T single nucleotide polymorphism (SNP) in PTPN22 encoding the R620W allele variant has been associated...