A2026 Effect of Anxiolytic Therapy on Blood Pressure in Elderly Patients with Hypertension in Flood Disaster Area

Abstract

Objectives: To investigate the changes of blood pressure fluctuation in elderly hypertensive patients in flood areas and the effects of anti-anxiety therapy on blood pressure related factors. Methods: The patients anesthesia group, which received conventional medical antihypertensive therapy while increasing the anxiolytic drugs and psychological counseling treatment; Control group were simply given conventional medical antihypertensive drugs. After 8 weeks of treatment, HAMA score, MBPS, BPV,PPI,AASI, CAP and PWV changes between the two groups. Results: 276 cases of elderly hypertensive patients have appeared the varying degrees of anxiety in the process of flooding and reconstruction, and blood pressure fluctuations along with it. After treatment for 8 weeks, the HAMA score, blood pressure variability (MBPS, short-term BPV) and PPI of the two groups were significantly improved (P < 0.05).And the improvement of HAMA score of the anxiolytic group was better than that of the control group (P < 0.05), as well as the blood pressure variability (MBPS, short-term BPV) and the improvement of PPI of the anxiolytic group were also better than those of the latter. However, the indexes of CAP, AASI and PWV in the two groups had no significant difference compared with those before treatment, the difference was not statistically significant (P > 0.05). Conclusion: Flooding and post-disaster reconstruction can easily cause different levels of anxiety in the elderly population, which may lead to the state of stress in elderly hypertensive patients. The elderly patients with hypertension who underwent flood and post-disaster reconstruction were treated with conventional antihypertensive therapy, as well as with anti-anxiety treatment and psychological counseling, which could effectively improve the clinical control of blood pressu