Abstract
Bioinformatics is becoming increasingly important in modern science, but opportunities to present this area to undergraduates are limited. I have prepared a web-based tutorial on fundamental concepts in bioinformatics that can be implemented in a variety of contexts in the undergraduate curriculum (introductory biology, biochemistry, molecular biology, etc). The Tutorial provides background information and exercises in five areas: (1) Searching the Scientific Literature (the most fundamental skill of all), (2) Finding the nucleotide sequence for a known gene in the GenBank database, (3) Determining the correct reading frame for an unknown DNA sequence, (4) Using BLAST to identify a putative reading frame, and (5) Searching for sequence motifs in a given protein. This site is designed to give students hands-on experience with some of the fundamental tools used in modern molecular biology and to help students move away from text-book based information sources and to the actual research tools. The site can be viewed at http://ase.tufts.edu/biology/bioinformatics/index.html. This site was developed with support of a Teaching with Technology grant from the Academic Technology department at Tufts University.
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