A water-stable zwitterionic Zn(II) coordination polymer as a luminescent sensor for the nitrofurazone antibiotic in milk

Abstract

The abuse of antibiotics has become a global problem because it has caused many serious environmental problems and threatened human health. Therefore, the selective and sensitive detection of antibiotic residues is important. In this work, a novel coordination polymer, {[ZnL1.5(H2O)]·(ClO4)2·3H2O} (CP 1), was constructed under hydrothermal conditions using a zwitterionic organic ligand (1,1′(2,3,5,6-tetramethyl-1,4-phenylene)bis(methylene)bis(4- carboxypyridin-1-ium)chloride (H2LCl2)). CP 1 was characterized by single-crystal X-ray diffraction, powder X-ray diffraction, FT-IR spectroscopy, elemental analysis and thermal gravimetric analysis. Among the different classes of antibiotics, CP 1 can selectively and efficiently recognize the nitrofurazone (NZF) antibiotic with low limit of detection (0.012 μM). CP 1 showed good selectively, strong anti-interference and powerful recyclability in the detection of the NZF antibiotic. As a sensitive sensor, CP 1 can detect NZF in milk, and a perfect recovery (97.40 %–103.05 %) was acquired. Additionally, the fluorescence quenching mechanism was attributed to fluorescence resonance energy transfer and photoinduced electron transfer.