Abstract
A versatile radioimmunoassay for serum oestriol in pregnancy has been developed which requires 10 μ| of serum (for total) or 50 μ| (for unconjugated). Selection of the optimum conditions for the hydrolysis of serum oestriol conjugates, the isolation of free oestriol, the displacement of tritiated oestriol by cold oestriol and the separation of the free and bound fractions is described. Total oestriol levels doubled between weeks 34 and 38 of normal pregnancy, very little change occurring in the mean level after the 38th week of gestation. In a random series of pregnancy sera there was a significant correlation between total and unconjugated oestriol.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Annals of Clinical Biochemistry: International Journal of Laboratory Medicine
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
