A turn-on fluorescence molecularly imprinted sensor based on covalent organic framework for specific and visual detection of α-dicarbonyl compounds

Abstract

In this paper, a turn-on fluorescence sensor (COFTPDD@ILMIPs) was prepared for the detection and removal of the α–dicarbonyl compound 3-deoxyglucosone (3-DG) in milk. The sensor uses ultra-high quantum yield green fluorescent covalent organic frameworks (COFs) as the fluorescence center, and introduces ionic liquids to improve its fluorescence performance and mass transfer rate, and the selectivity and anti-interference ability of the sensor were improved by molecular imprinted technique. In addition, the sensor was combined with a smartphone sensing platform to achieve real-time quantitative detection of 3-DG in the field. The quantitative detection of 3-DG in a good linear range (0.5–100 μg/L) was observed, and the low limit of detection was 0.31 μg/L. The spiked recoveries of 3-DG in milk samples ranged from 81.96–117.39 %, which provided an effective strategy for the accurate and rapid detection of hazardous substances in milk.