A total scoring system and software for complex modified GAPI (ComplexMoGAPI) application in the assessment of method greenness

Abstract

Evaluating analytical methods with innovative metrics is essential to ensure the effectiveness of analytical procedures. Various approaches have been proposed to assess the performance of an analytical method and its environmental consequences, as sustainable environment and green chemistry ideology are of high importance nowadays. Considering greenness evaluation of developed analytical procedures, Green Analytical Procedure Index (GAPI), one of these metrics, utilizes five distinct colored pentagons to evaluate the environmental footprint of the analytical process at different stages. An additional tool named Complementary Green Analytical Procedure Index (ComplexGAPI) was introduced to expand on GAPI by adding additional fields pertaining to the processes performed prior to the analytical procedure itself. Nevertheless, the existing ComplexGAPI lacks a comprehensive scoring system for individual methods, which would allow for even easier comparison of procedures using this tool. In response to queries from ComplexGAPI users, this study introduces a refined tool named ComplexMoGAPI, merging the visual appeal of ComplexGAPI with precise total scores. The accompanying software streamlines the application, facilitating quicker and simpler evaluations. This software is available as an open source on bit.ly/ComplexMoGAPI. We believe that, following ComplexGAPI success, this ComplexMoGAPI tool will also gain attention and eventually trust and acceptance from the chemical community.