Abstract
The respiratory activity of poultry is highly susceptible to changes in respiratory dead space volume, airstream pressure, ambient temperature, and body position. A technique has been developed which will minimize these variables; yet permit the exposure and detection of inhaled aerosols.Monodispersed latex spheres of a known size are radioactively labeled following polymerization of iodine-127 onto the surface of the spheres. The bird is anesthetized and placed in a whole-body plethysmograph. The liquid dispersed latex spheres are aerosolized from a nebulizer attached to a 10 p.s.i.g. compressed air line. The particles are electrostatically neutralized and routed to a plenum at near ambient pressure. The bird breathes at will through a unidirectional mask attached to the plenum.Following exposure the bird is euthanatized, the plethysmograph calibrated and the deposition in the respiratory tract measured at each of seven sections by a collimated, scintillation detector.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have