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https://doi.org/10.1126/science.358.6366.1015-i
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Cite Journal: Science |  Publication Date: Nov 23, 2017 |
Cancer Despite the explosion of research on chimeric antigen receptor (CAR) T cell therapy, most preclinical studies use transduced human T cells in immunodeficient mice. To determine how CAR activity is affected by T cell receptor (TCR) engagement, Yang et al. used a CAR targeting CD19 and
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