A Survey on Ocular in Situ Gel: An Original Medication Conveyance Framework

Abstract

In medication delivery system for the eyes the difficult part is to administer drug to the complex anatomical structure of eye. The residence time and bioavailability are the two major problems in conventional ophthalmic drug delivery system while designing a dosage form (eye drops, eye lotions, eye ointments) in order to address eye conditions. To combat these problems a novel drug a technique for delivering drugs termed In Situ Gel eye medication has been developed. Delivery system which is safe easy and effective. Furthermore bioavailability, precorneal residence duration can be increased and frequency of administration, side effect, drug loss owing to tearing can be decreased. In-situ gel production system are methods of delivering drugs that, before being administered to the body, are in solution form but require in situ gelation to change into a gel when activated by environmental stimuli including temperature, pH, and other factors.