Abstract

It is known that statistically significant (positive) results are more likely to be published than non-significant (negative) results. However, it has been unclear whether any increasing prevalence of positive results is stronger in the “softer” disciplines (social sciences) than in the “harder” disciplines (physical sciences), and whether the prevalence of negative results is decreasing over time. Using Scopus, we searched the abstracts of papers published between 1990 and 2013, and measured longitudinal trends of multiple expressions of positive versus negative results, including p-values between 0.041 and 0.049 versus p-values between 0.051 and 0.059, textual reporting of “significant difference” versus “no significant difference,” and the reporting of p < 0.05 versus p > 0.05. We found no support for a “hierarchy of sciences” with physical sciences at the top and social sciences at the bottom. However, we found large differences in reporting practices between disciplines, with p-values between 0.041 and 0.049 over 1990–2013 being 65.7 times more prevalent in the biological sciences than in the physical sciences. The p-values near the significance threshold of 0.05 on either side have both increased but with those p-values between 0.041 and 0.049 having increased to a greater extent (2013-to-1990 ratio of the percentage of papers = 10.3) than those between 0.051 and 0.059 (ratio = 3.6). Contradictorily, p < 0.05 has increased more slowly than p > 0.05 (ratios = 1.4 and 4.8, respectively), while the use of “significant difference” has shown only a modest increase compared to “no significant difference” (ratios = 1.5 and 1.1, respectively). We also compared reporting of significance in the United States, Asia, and Europe and found that the results are too inconsistent to draw conclusions on cross-cultural differences in significance reporting. We argue that the observed longitudinal trends are caused by negative factors, such as an increase of questionable research practices, but also by positive factors, such as an increase of quantitative research and structured reporting.

Highlights

  • The abundance of positive results in the scientific literature It is well known that the distribution of p-values in the scientific literature exhibits a discontinuity around alpha = 0.05, with p-values just below 0.05 being more prevalentHow to cite this article de Winter and Dodou (2015), A surge of p-values between 0.041 and 0.049 in recent decades

  • 3,061,170 papers belonged to the social sciences, 14,412,460 papers belonged to the biological sciences, and 15,364,142 papers belonged to the physical sciences

  • We investigated longitudinal trends of positive versus negative results reported in the literature and compared these trends between scientific disciplines and between world regions

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Summary

Introduction

The abundance of positive results has often been attributed to selective publication, called the file drawer effect (Dwan et al, 2008; Hopewell et al, 2009; Rothstein, Sutton & Borenstein, 2006). Another explanation for the discontinuity in the p-value distribution is that many statistically significant findings in the literature are false positives. A highly-cited article by Ioannidis (2005) claimed that over 50% of the published results that are declared statistically significant are false, meaning that they are negative (i.e., null) effects. Concerns regarding publication bias and false positives have been expressed in a variety of research fields, including but not limited to biology and ecology (Jennions & Møller, 2002), economics (Basu & Park, 2014), medicine and pharmaceutics (Dwan et al, 2008; Hopewell et al, 2009; Kyzas, Denaxa-Kyza & Ioannidis, 2007), neurosciences (Jennings & Van Horn, 2012), epidemiology (Pocock et al, 2004), cognitive sciences (Ioannidis et al, 2014), genetics (Chabris et al, 2012; Ioannidis, 2003), and psychology (Ferguson & Heene, 2012; Francis, 2013; Francis, 2014; Franco, Malhotra & Simonovits, 2014; Laws, 2013; Simmons, Nelson & Simonsohn, 2011)

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