A surface plasmon resonance system for the measurement of glucose in aqueous solution

Abstract

In this paper, a surface plasmon resonance (SPR) system is proposed as an alternative approach for glucose measurement. The developed SPR system, which is based on wavelength interrogation technique, has a high detection resolution of 8.67×10 −6 refractive index unit (RIU), equivalent to 6.23 mg/dL of glucose in water. The experimental results show that the proposed SPR system is capable of measuring the glucose at the concentration levels in physiological ranges, potentially leading to its further development towards a minimal-invasive glucose measurement of interstitial fluid.