A STUDY TO DETECT THE PROPORTION OF ALTERED SERUM CALCIUM, PHOSPHOROUS AND VITAMIN D3 LEVEL IN NEWLY DIAGNOSED PULMONARY TUBERCULOSIS PATIENTS ATTENDING CHEST OPD IN BURDWAN MEDICAL COLLEGE & HOSPITAL

Abstract

Introduction: Pulmonary Tuberculosis (PTB) is still a very common cause of morbidity & morbidity in India.[7] Calcium and phosphorus metabolism plays an important role in the healing of lesions in PTB. Vitamin D deficient individuals have a greater susceptibility to develop TB[14] and worse disease progression if infected with TB.[15] Due to paucity of studies this study was carried out to estimate the mean value of serum calcium phosphorous and Vitamin D3 level in newly diagnosed PTB patients and find out correlation among the altered values of these biochemical parameters.
 Methods: This was an observational cross sectional hospital based study carried out on 120 patients attending Burdwan Medical College over a period of one and a half years. All patients of PTB were included, while patients with Sarcoidosis, hepatitis, chronic kidney disease, post menopausal women were excluded from study. Serum Calcium, Phosphorus and Vitamin D3 were estimated in these patients. Data collected was entered in Excel Spreadsheet, and analysed in SPSS version 19.0 using descriptive statistical methods, percentiles and scatter diagrams.
 Main Findings: Serum calcium and phosphorus was not significantly decreased in our study. Moderate prevalence of vitamin D deficiency was found among newly diagnosed PTB patients. Significant correlation was found between altered vitamin D3, serum phosphorus and serum calcium level.
 Conclusion: Since Serum vitamin D3 is significantly decreased in pulmonary tuberculosis it is essential to monitor the serum levels of vitamin D3 in PTB patients and provide adequate supplementation of vitamin D3.
 Keywords: Pulmonary Tuberculosis, Calcium, Vitamin D3, Phosphorus