Abstract
This paper mainly studied the effect of ethanol extract of Radix rhapontici on erythrocyte immune function in SD rats with acute blood stasis. The methods used the effect on erythrocyte immune function. After intragastric administration of suspension of ethanol extract of Radix rhapontici to SD rats for 3 weeks, on the 21st day from intragastric administration, SD rats were made into blood stasis model and bloods were collected to determine the C3b, C3bRR, RFIR, and RFER in erythrocyte immune function. Meanwhile, serum total antioxidant activity (TAA), superoxide dismutase (SOD) activity, and serum malondialdehyde (MDA) level of rats were determined, and experimental results were analysed with analysis of variance and Q test. The results showed that the ethanol extract of Radix rhapontici had a very good effect on enhancement of erythrocyte immune function in SD rats.
Highlights
Radix rhapontici is the dried root of Rhaponticum uniflorum (L.) DC., which belongs to the Asteraceae family
The data of Radix rhapontici ethanol extract groups showed that the high-dose group had obvious changes compared with the low-dose group, and had statistically significant differences compared with the model group
There has been a study which used a mice hyperlipidemia model established using 75% egg yolk emulsion to demonstrate very significant increase in HDL-C (P
Summary
Radix rhapontici is the dried root of Rhaponticum uniflorum (L.) DC., which belongs to the Asteraceae family. It is mainly grown in places such as Hubei, Liaoning and Shanxi. It is collected in spring and autumn. Pharmacology studies have shown that the extract of Rhaponticum uniflorum (L.) DC., a plant in this genus, has multiple effects such as antifungal, anti-atherosclerotic, anti-lipid peroxidation and immune function improvement. This paper mainly studies the effect of Radix rhapontici extract on erythrocyte immunity in rats, laying the foundation for future development of valuable drugs for immunity improvement
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