A STUDY ON COMPARISON OF BLOOD GROUPS IN COVID 19 INFECTED AND NON INFECTED MBBS STUDENTS OF AIIMS UDAIPUR

Abstract

Background: - (COVID-19) is an infectious pandemic disease affected people of all age and gender but still there was variation in susceptibility and severity. ABO blood group was considered as a susceptible factor. There is a discrepancy and paucity of data regarding the relationship between ABO and Rh blood typing and susceptibility to COVID-19 disease. Aims and objectives:- To identify the blood groups of all our study subjects and then to compare blood groups among Covid infected and non-infected medical students. Lastly to motivate our study subjects to donate blood. Materials and methods:- Apparently healthy 287 MBBS students aged between 18-25 years were selected as subjects of our study. Ethical clearance was taken from institutional ethical committee. Consent was taken from all study participants. Blood groups were determined during regular physiology practicals and cross veried with their identity cards. Detailed history was obtained regarding Covid 19 disease and two groups were formed as Covid infected [45] and non -Covid infected[242] and then the blood groups of both these group subjects were compared and statistically analysed using SPSS 22.0 statistical software and R environment version 3.2.2 Results:- we found that blood group B positive was majorly distributed and least susceptible among the Covid 19 non- infected individuals. The O positive blood group was predominantly distributed and most susceptible among Covid 19 infected individuals Discussion & conclusion:- ABO gene is highly polymorphic and blood types have considerably different distribution across ancestry groups and geographic location. ABO and Rh groups are not distributed equally across, race or ethnicity groups. Large sample size and prospective type of study is required to exactly explain the blood group association with disease susceptibility