​A Study on Alteration in Serum Biochemical Parameters in Colibacillosis Affected Diarrhoeic Cattle Calves

Abstract

Background: The objective of the present study was to evaluate the changes in serum biochemical parameters in colibacillosis affected diarrhoeic cattle calves below one month of age. Methods: The study was undertaken at Veterinary Clinical Complex, College of Veterinary and Animal Science, Rajasthan University of Veterinary and Animal Sciences, Bikaner, Rajasthan, India, during the period from September 2018 to March 2019. A total of 32 calves affected with colibacillosis confirmed on the basis of Multiplex PCR (for presence of K99, Stx1 and eaeA genes of E. coli) and eight clinically normal healthy calves (as control) were taken to investigate the serum biochemical profiles. Result: Analysis of serum samples of calves affected with colibacillosis revealed significant increase in the values of total protein, albumin, globulin, A/G ratio, blood urea nitogen, creatinine, potassium, total oxidant status andoxidative stress index while there is a significant decrease in the values of glucose, sodium, chloride, bicarbonate, IgG, IgM and total antioxidant status. There were no significant changes observed in the values of ALP, AST and ALT in affected calves as compared to healthy control group of calves.