A study of variability in detrusor overactivity of different types on repeated filling cystometry

Abstract

Objective To evaluate the variability in detrusor overactivity of different types on repeated filling cystometry.Methods The repeated filling cystometry were performed in 78 male patients who had presented with detrusor overactivity(DO)in the urodynamic studies during the period of February 2006 to June 2012,including 41 spinal cord injury(SCI)patients and 37 benign prostatic hyperplasia (BPH)patients.DO was defined as occurrence of involuntary detrusor contractions(IDC)during filling cystometry.All of the patients had undergone a second filling cystometry 10 minutes after the first filling cystometry completed.The urodynamical parameters were recorded as the first sense volume of bladder,the maximum bladder capacity,Q the detrusor pressure at Q the volume at the first involuntary detrusor contraction(IDC),the maximum IDC amplitude,IDC number in the first and the second filling cystometry separately.The urodynamical parameters were compared between the first and the second filling cystometry in SCI and BPH patients separately.Results In SCI patients,differences of urodynamical parameters between the first and the second filling cystometry were not significant(P＞0.05).In BPH patients,the first sense volume(120.0±40.2 ml and 112.3±42.1 ml)was larger(P=0.00),the maximum capacity(307.5±73.3 ml and 295.4±82.5 ml)was larger(P =0.01),the volume at the first IDC(146.2±43.9 ml and 134.3±48.2 ml)was larger(P=0.00),and IDC number(2.2±1.5 and 2.8±1.3)was reduced(P=0.00)in the second filling cystometry compared with the first filling cystometry.5 out of 37(13.5％)BPH patients did not demonstrate DO in the second filling cystometry.Conclusions The variability of detrusor overactivity varies in different type of detrusor overactivity.Neurogenic detrusor overactivity is stable,and idiopathic detrusor overactivity has a tendency of alleviation on repeated filling cystometry. Key words: Urodynamics; Pressure-flow study; Detrusor overactivity; Variability