Abstract
Iodine solution is the only contrast medium currently used in the computed tomography scan (CT scan) examination. In the present study manganese chloride (MnCl2) solution has been chosen as alternative contrast medium in computed tomography scanning (CT scan). It was found that using MnCl2 solution as an alternative contrast medium in rabbits which enhanced the CT scan imaging in the resolution and increasing the Hounsfield unit (HU) values of heart and kidney organs in comparison with the iodine compound at the same doses. It was chosen the heart and kidney of rabbits to study the effect of using the iodine and MnCl2 solution as alternative contrast medium in CT scan imaging, the following results: the native has 45 HU for heart and 50.1 for kidney organ. While the results of using iodine solution at dose of 3 ml has 83 HU for heart and 164 HU for kidney organ. In the MnCl2 solution which used as alternative of contrast medium has 83 HU for heart and 70.3 HU for kidney at 2.5 ml of 0.5 molar of solution. From these results the resolution of CT scan image has well and clears when using the alternative contrast medium (MnCl2). We can concluded that the alternative contrast medium of MnCl2 solution has good HU values of both heart and kidney comparison with iodine solution.
Highlights
Through the different studies of alternatives to the contrast media which used in different radiological techniques that have important effects on human health and to avoiding the side effects from the use of current contrasts media such as iodine and gadolinium harmful to the health [1,2,3,4]
The second group, in which the spatial survey of rabbits was studied using an alternative contrast medium for manganese chloride solution, where the kidneys and heart of rabbits were studied via intravenous manganese chloride alternate contrast at a concentration of 0.5 mol at different doses (1, 1.5, 2, and 2.5 ml) and the tests were performed following using CT scanning
computed tomography scan (CT scan) examination of heart organ This examination was taken for all members of the abdominal area of the body of the rabbits such as kidney and heart without using any contrast media, the iodine contrast and the alternative contrast (MnCl2 solution) were used for the examination was taken for the heart and kidney organs in the rabbits
Summary
Through the different studies of alternatives to the contrast media which used in different radiological techniques that have important effects on human health and to avoiding the side effects from the use of current contrasts media such as iodine and gadolinium harmful to the health [1,2,3,4]. Manganese was one of the earliest reported examples of paramagnetic contrast materials for magnetic resonance imaging due to its positive active contrast enhancement [5]. Manganese-enhanced magnetic resonance imaging (MRI) is a well-established neuroimaging method for signal enhancement, and functional studies in the rat. With the increasing availability of positron tomography (PET) and magnetic resonance imaging devices, interest in using Mn2 + as a contrast agent. Contrast enhancement of manganese-based contrast agents was evaluated in mice carrying with human breast cancer xenografts, compared with MnCl2 [7]. Clinical applications of manganese-based MRI contrast agents are intravenous (intravenous) and oral formulations. The enhancement of computed tomography imaging by chemical contrast media was studied by using an alternative of iodine contrast agent of a manganese compound.
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