A study of the poly(dA)-poly(dT) DNA electric field-dependence: density of states (DOS) analysis

Abstract

Study of poly(dA)-poly(dT) DNA molecule electronic structure, by analysing its density of states (DOS), had been conducted. This research employed Green’s function method as tool to determine electron DOS of the DNA numerically. Electric field that was applied along z-axis is used as perturbation to modify electron hopping constant between sites in the molecule. In order to include electric field in the calculation, Miller-Abraham formula was used. Medium interaction with backbone molecules was considered as well within the calculation in the form of backbone disorder. By increasing electric field, the band in electron DOS spectrum appeared to become narrower and several states experience the decrement of DOS.