Abstract
Although many studies have been made with surface-active agents, most of the work has not been primarily concerned with any effect they might have on immunological systems. Some investigators have used changes in electrophoretic mobilities of bacteria as a measure of the effect of surface-active agents upon bacterial surfaces (Dyar and Ordal, 1), (Kivela et al., 2). Holmes (3) introduced alcohols, soaps, and esters into serological systems and found that the soaps and three of the esters employed inhibited serological reactions. Cohen (4) used benzene sulfonyl chloride to treat Proteus OX-19 and noted that treated organisms failed to agglutinate. Immunochemical studies of surface-active-agent-treated proteins have been made by Engley and Glassman (5). Avidor and Yaniv (6) found that the addition of Cetavlon to virulent strains of Pasteurella tularensis did not influence
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