Abstract
Radioactive sources in brachytherapy are placed near or within the target. Therefore, it requires the optimum dose distribution to decrease the dose at the organ risk. The human body is composed of many different densities of tissues. However, in a clinical calculation, the human body is assumed as homogeneous. This study aims to analyze dose distribution from Ir-192 source on the inhomogeneous medium using Monte Carlo simulation. We used DOSXYZnrc program and applied the parameters to generate the dose distributions. The parameters were; (a) a water phantom of volume 20 x 20 x 20 cm3, (b) an inhomogeneous phantom of volume 1 x 1 x 4 cm3, (c) the voxel of volume 0.2 x 0.2 x 0.2 cm3, and (d) the simulation parameters ECUT 0.521 MeV, PCUT 0.01 MeV, and 1x108 the number of particles. Nine of the Ir-192 line sources distributed at certain coordinates. The results were analyzed by the isodose curves. According to isodose curves, we derived the distance from 75% to 100% of relative dose respectively 0.4 cm and 0.6 cm for water phantom and inhomogeneous phantom. The inhomogeneous phantom received less 0.02 Gy dose than the water phantom. The study conclusion is that the presence of an inhomogeneous medium can affects the dose distribution change.
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