Abstract
The influence of particle size and particle size distribution on permeability and hydrodynamic dispersion was studied as the first stage in the development of a numerical model of chromatographic processes. Permeability and hydrodynamic dispersion were measured and models were tested against the data obtained. The influence of the chromatographic column wall was minimized by using a wide column (d = 0.113 m). Nonporous glass beads of different sizes (d p(mean) = 125–250 µm) and size distributions (SD/d p(mean) = 0.06–0.21) were used as packing material. The longitudinal dispersion was measured between Pep numbers 3 and 430 by recording the response of a sodium chloride step input at four radial positions at each of three levels of electrodes inside the column. Permeability was measured at the same time; the Rep numbers lay between 0.004 and 0.6.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
