Abstract

Objective: Diabetes Mellitus is a group of common metabolic disorders that share the phenotype of hyperglycemia. Several distinct types of Diabetes Mellitus exist and are caused by interaction of genetics and environmental factors. Individuals with Diabetes Mellitus may develop signs of autonomic dysfunction involving cholinergic, noradrenergic and peptidergic systems. Type 2 Diabetes Mellitus has a strong genetic component. Individuals with a parent with Type 2 Diabetes Mellitus have an increased risk of Diabetes. If both parents have Type 2 Diabetes Mellitus, the risk approaches to 40%. Thus this study is designed to evaluate glycemic status and autonomic functions in nondiabetic offsprings of Type 2 diabetic parents. Method: The cross-sectional study of Glycemic status and Cardiovascular Autonomic Functions was carried out in 30 healthy offsprings of Type 2 Diabetic Parents (Study group) and 30 healthy offsprings of Nondiabetic Parents (Control group) in the age range of 18 - 21 years randomly selected among 1st MBBS students. Statistical Analysis is done by

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