Abstract
Aim/purpose: To study and correlate the change in retinal thickness with age and to establish a clinical importance between the two factors. A number of 50 healthy subjects between the ages of 18-65 years on outpatie Methods: nt basis were taken and evaluated. Pupils of the subjects were dilated with tropicamide 0.8% and OCT Optic Disc scan was performed on each eye using the Cirrus HD OCT 500. The total retinal thickness and retinal nerve fiber layer (RFNL) thickness were noted. Out of the 50 subjects, 48% of them were female and 52% of them male. The mean RESULTS: retinal thickness was 234.78 μm ± 16.07 with a coefficient of variation of 6.8%. The mean RFNL was 84.6 μm ± 20.67 with a coefficient of variation of 24.4%. Linear regression plots are done using x variable as age and y variable as RFNL/Total retinal thickness and using the formula Y = mx + b, it is plotted against a graph for each of the two variables. Unpaired t test used, t = 13.8599. The value P<0.001 and was considered statistically significant. According to CONCLUSION: this study, retinal thickness significantly decreases with age. Hence, it is important to perform OCT as a screening process in older individuals to rule out diabetic changes, macular edema, to detect thinning of the retina in myopics as a risk factor for RD and to rule out other pathologies.
Published Version
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