Abstract

Magnetic detection electrical impedance tomography (MDEIT) is a novel imaging technique that aims to reconstruct the conductivity distribution with electrical current injection and the external magnetic flux density measurement by magnetic sensors. Aiming at improving the resolution and accuracy of MDEIT and providing an efficient imaging method for breast cancer diagnosis, a new algorithm based on stacked auto-encoder (SAE) neural network is proposed. Both numerical simulation and phantom experiments are done to verify its feasibility. In the numerical simulation, an amount of sample data with different conductivity distribution are calculated. Then a neural network model is established and trained by training these samples. Finally, the conductivity distribution of an imaging target with the anomaly location can be reconstructed by the network model. The reconstruction result of the SAE algorithm is compared with the reconstruction results of the traditional sensitivity matrix (SM) algorithm and the back propagation (BP) neural network algorithm. Under the noise of 30dB, the relative errors of BP algorithm, SM algorithm and SAE algorithm are 137.19%, 24.90% and 15.28% respectively. Result shows by the SAE algorithm, the location of anomalies is reconstructed more accurately, the conductivity value is more closely to the real one and the anti-noise performance is more robust. At last, a breast phantom experiment by self-made platforms is completed to verify the application feasibility of the new algorithm. The relative reconstruction error of conductivity by proposed SAE algorithm can be reduced to 14.56%. The results show that by SAE algorithm, MDEIT can be a promising approach in clinical diagnosis of breast cancer, and it also provide more potential application prospect for the extensive application of MDEIT.

Highlights

  • Breast cancer is one of the most common cancers among women in the world [1]

  • stacked auto-encoder (SAE) ALGORITHM FOR INVERSE PROBLEM In order to realize the reconstruction of conductivity distribution by the magnetic field measurement data, this paper proposes a SAE neural network algorithm connected with softmax classifier to solve the inverse problem of Magnetic detection electrical impedance tomography (MDEIT)

  • The results show that by the SAE algorithm, the anomalies at different positions can be accurately located in the imaging body

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Summary

INTRODUCTION

High precision of medical imaging modalities is required to discriminate tumors in early time diagnosis for breast cancer. Convolutional neural network (CNN) is proposed to solve inverse problem of the electrical resistance tomography (ERT), the accuracy of reconstructed image is improved and the reconstruction time is shortened [25]. According to the previous research, a multi-input multi-output MDEIT imaging algorithm based on stacked auto-encoder (SAE) neural network is proposed to solve the reconstruction of the inverse problem. The main purpose of the proposed SAE neural network algorithm is to significantly improve the quality of the image and the speed of reconstruction. The SAE algorithm effectively improves the ill-posed of MDEIT inverse problem It provides a new and promising approach for MDEIT image reconstruction. It provides a fast and high-precision imaging method for the diagnosis of breast tumors

BASIC AND KEY TECHNOLOGIES
FORWARD PROBLEM IN MDEIT
SENSITIVITY MATRIX ALGORITHM FOR INVERSR PROBLEM
BP NEURAL NETWORK ALGORITHM FOR INVERSE PROBLEM
RESULTS
DISSCUSSION
CONCLUSION
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