Abstract
Drug Solvation Although we brew coffee and tea in water, the psychoactive drug we crave, caffeine, is moderately hydrophobic and becomes more so as the temperature of a beverage decreases. Stacked aggregates of caffeine molecules, which may have different properties, can form at saturation. Shumilin et al. investigated the distribution of caffeine aggregates and monomers in response to increasing concentration of a common excipient: sugar. Although various sugars decreased overall caffeine solubility, they had a preferential effect on oligomers and resulted in a higher relative proportion of caffeine in the monomer form. J. Am. Chem. Soc. 141 , 18056 (2019).
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
