Abstract
3551 Background: Although the recent advances in surgury and chemotherapy have enabled hepatectomy in patient with initially unresectable colorectal liver metastases (CRLM), limited number of patients could actually benefit from this strategy. The aim of this study was to develop a simplified nomogram to predict long-term survival for initially unresectable CRLM treated with conversion chemotherapy followed by hepatectomy. Methods: From a cohort of 1275 patients who underwent hepatectomy between 1990 and 2012, 439 patients (34.4%) with initially unresectable CRLM were enrolled in this study. A nomogram to predict overall survival was developed based on the result of multivariate cox model. The predictive performance of the model was assessed by C-index, Kaplan-Meier curve, and calibration plots. Results: The median number of liver metastases was 5 both at diagnosis and at hepatectomy, and median tumor size was 50 mm at diagnosis and 35 mm at hepatectomy, respectively. Median number of preoperative chemoth...
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
