Surgical Outcome of Colorectal Cancer Liver Metastases in Our Facility: Efficacy of Conversion Surgery in Initially Unresectable Colorectal Liver Metastases

Abstract

Recent advances in modern chemotherapy, targeted drugs, and expanded indications of hepatectomy have improved overall survival (OS) and disease-free survival (DFS) after hepatectomy of colorectal liver metastases (CLM). This chapter describes our experiences and strategy for CLM and the surgical outcomes of our patients. Consecutive 141 patients with CLM managed in our department were reviewed in this study. The 5-year OS and DFS achieved in this study were 51.1% and 26.7%, respectively. Only synchronous CLM and lymph node positivity in the primary lesion predicted adverse DFS. Conversion hepatectomy for initially unresectable CLM was notably effective, with similar OS and DFS as in initially resectable CLM. Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) seemed effective for the challenging resection of advanced CLM.