Abstract
MeBmt 1 was prepared in four steps from the optically pure (2Z, 4R) 4-methyloct-6-yn-2-en-1-ol 8, Z allylic alcohol containing an alkynyl group at the γ position. The two stereogenic centers C-2 and C-3 in the product were controlled using Sharpless' epoxidation and subsequent ring opening at C-2 of the epoxy acid 10 with methylamine.
Published Version
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