Abstract
The sesquiterpene arenarol (1) was isolated from the marine sponge, Dysidea sp. by supercritical fluid extraction and reversed-phase high performance liquid chromatography. The molecular structure was elucidated on the basis of 1H and 13C-NMR chemical shifts. The isolated secondary metabolite exhibited a very week antimitcrobial activity at 15 ug against Staphylococcus aures, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa, and showed a DNA-binding property with a retention factor ratio of 0.76 by one dimensional thin-layer chromatography.
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