Abstract

Due to intestinal dysbiosis brought on by second-line anti-tubercular medication therapy, the patient's resistance to MTB appears to have decreased. This is likely due to an impact on immune cell proliferation and autophagic processes. therefore adversely influencing the patients' treatment results. The objectives of review articles are the safety and efficacy on the second line anti tubercular drugs. The results of these review article in the year 2015 to 2020. The conversation of these review article is the safety and efficacy of second line anti tubercular drugs . The discussion of these study about the safety and efficacy on second line anti tubercular drugs . 2016 levofloxacin is a not more safe and less effective because result insufficient control to the tuberculosis patient it adverse events is underactive thyroid. 2020 Ethionamide is a safe and effective for the TB patients. The conclusion of these review study and efficacy of the second line anti tubercular drugs. The ofloxacin are the most effective and safe when compared to the other second line anti tubercular drugs. In second line anti tubercular drugs the levofloxacin is having the less efficacy when compared to other second line anti tubercular drugs because it is having the adverse effect of the hypothyroidism. For the treatment of tuberculosis the drugs used are the levofloxacin, kanamycin, etc and these are most commonly used for the prevention of the disease.

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