A Review Study on Monitoring of Physiological Parameters for Ocular Diagnostics and Administering Drugs for Ocular Diseases through a Contact Lens (A Wearable Device)

Abstract

To describe the various types of diagnostic utilization (physiological parameters) of contact lens-based sensors and administering drugs for ocular diseases. The early diagnosis of ocular diseases is greatly helped by contact lens sensors. Since the lacrimal fluids include biomarkers, contact lens sensors can be used to do non-invasive direct measurements of a variety of parameters, including corneal temperature, pH, intraocular pressure (IOP), proteins, nitrite, and chloride ions. Wearers can conduct self-examinations at home using smartphones owing to microfluidic contact lens sensors that are based on colorimetric detection and liquid control mechanisms. A Narrative review was done to review the articles available on PubMed, Google Scholar, Medline, Publon, Orcid, Healthstar, and others related to contact lens sensors and drug-administering for ocular diseases. Peer-reviewed articles/ studies were referred to ascertain the available screening tests, contact lens sensors, physiological parameters, and diagnosis of glaucoma, diabetic retinopathy, and others. This review study provides an overview of the contact lenses for ocular diagnostics and delivering drugs for ocular diseases. Thus, soft contact lenses can be used to diagnose specific disorders as well as deliver medications, which have advantages over traditional eye drops in terms of prolonged residence duration and ocular bioavailability.