Abstract

Human skin has a major role in protecting several organs from various microbial attacks. It regulates the body’s temperature and its other normal functions. It is usually possessed by various microbes that may vary in different aspects and impacts on human dermal layer and may lead to serious infections in future. Encounter of human dermal layer to any injury or wound can be a forum for microbes to get entered and cause infection. Most of infections occur due to zoonosis. Anthropozoonosis, zooanthroponosis and amphixenoses are the terms acknowledged for transmit of disease or infections. Zoonosis has three major categories on the basis of type of host, etiological agents and life cycle of pathogens. Each category is further sub-categorized into various possible groups. Domestic animals are generally the primary source for humans to get infected. Human skin is affected by the virus, namely Orf zoonosis having corresponding to the genus Parapoxvirus. It is a major threat to human dermal layer.

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