Abstract

Over the past few years, the evolution of nanotechnology has extended into a wide range of applications. Nanotechnology has now become a multidisciplinary science that applies to electronics, materials science, biomedical engineering, microbiology, etc. Recently, nanotechnology is being used in biomedical and pharmaceutical science. Among them drug delivery is set to spread rapidly. Application of nanotechnology in health sector also created a potential impact such as in the fields of immunology, cardiology, endocrinology, ophthalmology, and oncology. Nanoparticles are unique because of their large surface area and it has the potential to change the properties of a bulk number of materials. The surface of nanoparticles can be modified with the help of various polymers, organic and inorganic substances according to the specific application and their use. Nanoparticles are also utilized as nano shells in drug delivery systems and cancer therapy. Nano shells can recognize the cancer cells when they are injected into the cancer area. The heat generated by the light absorbing nano shells due to the application of the near infrared light successfully kills tumour cells leaving the noncarcinogenic cells intact. In this review article, nanoparticles, the health implication of nanoparticles and their synthesis are discussed.

Highlights

  • Nanostructures and nanotechnology are an extensive and multidisciplinary areas of research and development activity that is increasing strenuously around the world

  • The branch nanotechnology is the science that deals with the processes that occur at the molecular level and of Nano length scale size multidisciplinary science covers several applications in other disciplines such as biophysics, molecular biology, and bioengineering

  • The first liposome-based therapeutic, liposome-encapsulated doxorubicin, for the treatment of HIV-related Kaposi’s sarcoma, and for the treatment of ovarian cancer and multiple myeloma was sanctioned by the US Food and Drug Administration (FDA) in 1995 [5,6,7]. This Review focuses on nanoparticles surface modification, composition, and applications of nanoparticles

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Summary

Introduction

Nanostructures and nanotechnology are an extensive and multidisciplinary areas of research and development activity that is increasing strenuously around the world. Nanotechnology is defined as a combination of science, engineering, and technology that is conducted at the nanoscale (1 to 100 nm), where the unique prodigies enable its applications in a different field, from chemistry, physics and biology, to medicine, engineering and electronic. The dimension in the nanometer scale are typically thin films or surface coatings, and include the circuitry of computer chips and the antireflection and hard coatings on eyeglasses These have been used in electronics, chemistry, and engineering. Materials that are Nano-scaled in all three dimensions are considered 3D nanomaterials These include thin films deposited under conditions that generate atomic-scale porosity, colloids, and free nanoparticles with various morphologies. Dendrimers, quantum dots, fullerenes (Carbon 60), (QDs) [15,16]

Properties of Nanoparticles
Physical Properties
Optical Properties
Magnetization Properties
Diffusion Properties
Surface Modification and Drug Delivery
Safety and waste Management
Precautionary Principle for Engineered Nanomaterials
Waste Management
Findings
Conclusion
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