Abstract
Over the past three decades, Gastric cancer risk and prevalence increased causing significant loss to human health worldwide. Mostly resistance developed highly to Surgery and chemotherapy against gastric cancer. Therefore, a need to the development of novel, low cost and efficient treatment methods. Phytoconstituents isolated from fruits are biologically active which attract the attention of pharmaceutical industries and researchers around the world. Pharmacological effects of bioactive compounds to fight against gastric cancer was proved by in vitro and in vivo studies Phytochemicals also regulate several molecular processes like cell cycle arrest, angiogenesis, apoptosis, autophagy, cell invasion and metastasis to combat gastric cancer. This review gives perspectives on key bioactive molecules bioaccessibility, availability and cellular mechanism of action in the gastric cancer. As well as, guide the public in developing functional food and drugs from phytochemicals for the prevention and treatment of gastric cancer.
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