A Review on Lung Cancer with Emphasis on Current Treatment

Abstract

Cancer is a broad term that refers to more than 277 types of cancer. It is a disease that results from a variety of causes, including mutations resulting from oncogene activation, tumor suppressor gene failure, or other factors. Mutations in these genes cause abnormal cell growth. Lung cancer is one of the leading causes of cancer in the world. Lung cancer, also known as lung cancer, is a lung disease caused by the uncontrolled growth of cells in tissues. Risk factors include smoking , exposure to radon gas, asbestos, secondhand smoke, and pollution. The two types of lung cancer are small cell lung cancer (SCLS) and non-small cell lung cancer (NSCLS). Common symptoms include cough, hemoptysis, weight loss, fatigue, fever or clubbing, hypercalcemia, myasthenic syndrome (muscle fatigue), and changes. Lung cancer is classified by histological type and stage using TNM (tumor, tumour, and metastasis). Treatment depends on the type of cancer and includes surgery, radiation and chemotherapy. Long-term intake of vitamin A, vitamin D, or vitamin E does not reduce the risk of lung cancer. Consuming more vegetables and fruits will reduce the risk. There is no clear link between diet and lung cancer. Most patients with advanced NSCLC who respond to surgery are treated with adjuvant chemotherapy. Histological diagnosis can be made by sputum cytology, thoracentesis, access to lymph nodes, bronchoscopy, transthoracic needle aspiration, video-assisted thoracoscopy or thoracotomy. Initial evaluation of metastatic disease is based on history and physical examination, chest examination, computed tomography, PET scan, and clear tissue of mediastinal involvement. Despite the interest in screening among scientists and doctors, there is no major organization recommending screening for early detection of lung cancer. Smoking is still an important part of primary prevention.