A Review of the effects Al-Madinah Al-Munawwarah Ajwa dates on several of E. coli producing extended spectrum beta-lactam

Abstract

Urinary tract infection (UTI) is the second most common disease after respiratory problems, it's also the most common infectious disease on a global scale in the field of health. The emergence of extended-spectrum beta-lactamase (ESBL)-producing E. coli (E. coli) resistance has led to a significant increase in urinary tract infections (UTIs) globally, this has posed a significant challenge. As a result, numerous investigations have been conducted with the goal of exploring botanical approaches to addressing the effects of antibiotic resistance in bacteria that cause diseases. Antibiotic resistance presents a formidable and pressing global challenge, requiring urgent and pivotal interventions to mitigate the spread of antibiotic-resistant bacterial strains. Date palms (Phoenix dactylifera L.) produce fruits that are popular throughout the world and are a significant part of the dietary culture in the Middle East. In the Kingdom of Saudi Arabia, dates have a significant role as a crop that's integral to the country's culture and heritage. The Ajwa date variety is distinguished by its elevated sugar content and large amount of dietary fiber, minerals, and vitamines. Its unique chemical composition that exhibits the potential to address multiple microorganisms that are resistant to antibiotics. Al-Madinah Al-Munawwarah is renowned for its production of rare dates exclusive to the region. Among the most famous types of date fruits found in Al-Madinah are Ajwah, Amberah, Majdool, and Safawi. These varieties are highly sought after for their distinct flavors and exceptional quality, contributing to the city's reputation as a hub for premium date production. The purpose of this review was to Study the effect of extracts from Ajwa date seeds on Extended-spectrum beta-lactamase of E. coli strains.