Abstract
A retrospective study on the relationship between annual airborne pollen levels during four decades of 1975–2014 and annual occurrence of ulcerative colitis, Crohn's disease, primary biliary cirrhosis, fulminant hepatitis, severe acute pancreatitis, interstitial pneumonia, amyloidosis, based on the national registry database of specific intractable diseases in Japan
Highlights
Ulcerative colitis (UC) and Crohn’s disease (CD) are major types of inflammatory bowel diseases (IBDs) [1]
This study aimed to show the trend for increase in Japanese IBD patients related to the amount of airborne pollen (AP) exposure, using an electronic database maintained by the Japan Intractable Diseases Research Foundation (JIDRF) under the Japanese Ministry of Health, Labor and Welfare’s nationwide registry system [2]
1975–2014, the upward peak of AP scatter in 1984-86 was found to be the earliest peak with which simultaneous outbreaks of multiple specific intractable diseases” (SIDs); all SIDs (ASIDs), UC, CD, FH, AMY, ITP, AA, and Kawasaki Disease (KD) were concurrent (Figures 1-3,5,8-11; Table 1)
Summary
Ulcerative colitis (UC) and Crohn’s disease (CD) are major types of inflammatory bowel diseases (IBDs) [1]. This study aimed to show the trend for increase in Japanese IBD patients related to the amount of airborne pollen (AP) exposure, using an electronic database maintained by the Japan Intractable Diseases Research Foundation (JIDRF) under the Japanese Ministry of Health, Labor and Welfare’s nationwide registry system [2]. This study examined 183 estimates from 53 meta-analyses of 71 environmental factors related to lifestyle, hygiene, surgeries, drug exposures, diet, microorganisms, and vaccinations This novel study on possible factors associated with IBDs showed varying levels of evidence on the relationship between different environmental factors and the risk of developing IBDs [4]. Systemic vasculitis such as Kawasaki Disease (KD) and collagen diseases have been suggested to be related to pollen exposure (PE)
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