Abstract

Prospective evaluation of cardiovascular-risk surrogates via lifestyle and adherence to the Mediterranean diet: Results from PERSEAS/The Elafonisos-Area Study

Highlights

  • Several epidemiological studies have demonstrated that metabolic risk-factors, such as hypertension, diabetes, and hyperlipidemia are associated with increased prevalence of cardiovascular complications [1,2]

  • Stroke incidence in Asian populations is by far higher compared with Europeans [12]; cardiovascular disease (CVD) incidence is higher in Northern-Europe compared with the Mediterranean-Sea [13]; and higher longevity is observed in well-confined areas of one country, as was demonstrated in IkariaIsland, Greece [14]

  • The present study demonstrated a marginal adherence to the Mediterranean-diet, and a high risk-factor prevalence in the rural population of Greece

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Summary

Introduction

Several epidemiological studies have demonstrated that metabolic risk-factors, such as hypertension, diabetes, and hyperlipidemia are associated with increased prevalence of cardiovascular complications [1,2]. Unhealthy lifestyle, described by physical-inactivity, increased alcohol consumption, imbalanced diet, and poor sleep, increases cardiometabolic-risk, and is closely associated with a higher prevalence, and incidence of cardiovascular disease (CVD) [5,6]. Even among regions, there is great variability in the prevalence of cardiovascular risk-factors, and the rate of complications [9,10]. This has been attributed to different lifestyle, and genetic background [11]. PERSEAS (Prospective Evaluation of vascular-Risk Surrogates: the Elafonisos-Area Study) is an epidemiological prospective study aiming to assess the physical course of cardiovascular risk-factors, including adverse lifestyle habits, and their complications in the closed rural area of Elafonisos-Island, Greece

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