A retrospective study on the management of osteoporosis in Parkinson's disease – A single institution, preliminary study

Abstract

PurposeThe aim of this study is to evaluate clinical characteristics of osteoporosis management in patients with Parkinson's disease. Materials and methodsData on patients with Parkinson's disease was collected from March, 2000 to March, 2013 at single institution. We investigated portion of BMD test, portion of diagnosed osteoporosis, portion of pharmacological treatment, prevalence and location of primary fractures and presence of second-fractures after primary fracture on in patients with idiopathic Parkinson's disease. ResultsTotal of 865 patients were included. Among the 865 subjects, the number of patients who underwent diagnostic studies was 189 (21.8%) and the number of patients who was diagnosed with osteoporosis with BMD test was 72 (38.1%), which was 8.3% of the whole patients. Among the patients diagnosed with osteoporosis, the number of patients who were administered with osteoporosis medication for more than 1 year was 49 (68.0%), which was 5.6% of the whole patients.One hundred thirty (15.0%) patients suffered from low energy fractures. Of the 130 fracture sites, 57(43.3%) occurred in proximal femur, 47 (36.1%) of in vertebra, 8 (6.1%) in wrist, 4 (3.0%) in proximal humerus and 14 (10.7%) elsewhere. Twenty two (16.9%) patients suffered from second fracture after the primary fracture. ConclusionIn Parkinson's disease patients, the diagnosis and pharmacologic treatment of osteoporosis were not done adequately, and thus both medical staffs and patients should take this matter into consideration.