A Retrospective Analysis of Clinical Features, Maternal and Neonatal Outcomes of COVID-19 patients in an Obstetric Clinic in Ankara, Turkey

Abstract

Objective: To evaluate the effects of coronavirus disease-2019 (COVID-19) infection on clinical and laboratory features; maternal and fetal outcomes. Material and Methods: In this retrospective study, the patients diagnosed with COVID-19 by positive severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) reverse transcription polymerase chain reaction (RT-PCR) and delivered at Koru Hospital (Ankara, Turkey) between March 2020 and February 2021 were included. We obtained demographic, clinical, laboratory features, obstetric and delivery history, maternal and perinatal outcomes from medical records. Results: Twelve pregnant patients were included in the study. The mean age was 32 years (range 28-43 years) and the mean gestational age at diagnosis of COVID-19 was 34 weeks (range 22 to 39 weeks 6 days), the mean gestational age at delivery was 38 weeks 4 days (range 35 to 40 weeks). All deliveries were as cesarean section. At first admission with suspicion of COVID-19, seven (58%) patients had fever, five (41%) patients had cough, two (16%) patients had dyspnea, two (16%) patients had anosmia and loss of taste, one (8.3%) patient had sore throat. None of the pregnant patients were taken to the intensive care unit before or after delivery. One neonate was tested for SARS-CoV-2 RT-PCR and the result was negative. Two neonates were admitted to neonatal intensive care unit due to preterm delivery of a twin pregnancy. Conclusion: COVID-19 infection has similar clinical characteristics in pregnant patients as in non-pregnants reported in the literature. The maternal, fetal and neonatal outcomes were good and vertical transmission seems unlikely.