Abstract
Abstract Introduction: Sarcoidosis is a multisystem inflammatory disease involving non-necrotizing epithelioid granulomas with an unknown etiology. Here we present a case of systemic sarcoidosis that involves the gastrointestinal tract. Patient concerns: A 45-year old Hispanic female initially presented with nonspecific symptoms including dysphagia and an unintentional weight loss of 65 lbs. Diagnosis: After extensive workup including endoscopy with biopsy, she was diagnosed with systemic sarcoidosis with gastrointestinal (GI), pulmonary and musculoskeletal involvement. Interventions: She was started on prednisone 60 mg daily and 15 mg of methotrexate subcutaneously with titration up to 22.5 mg. Outcomes: She has had significant improvement in symptoms. Currently her symptoms are well controlled on 22.5 mg of subcutaneous methotrexate weekly and folic acid 1 mg daily. She was seen by a pulmonologist who recommended monitoring with pulmonary function test and computed tomography chest every 6 months. Conclusion: In patients with known pulmonary sarcoidosis, nonspecific GI symptoms, and inconclusive tests, sarcoidosis with GI tract involvement should be considered.
Published Version
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