Abstract
Placental site trophoblastic tumor (PSTT) is a highly rare form of gestational trophoblastic diseases that arise from intermediate trophoblastic cells. By presenting this case, we aimed to review the treatment and diagnosis, approach to PSTT.A 31-year-old (G2P1A1L1) patient had abnormal vaginal bleeding. Serum ß-HCG was 5.82 mIU/ml and the transvaginal USG detected a polypoid mass in uterine cavity. Probe curettage was performed. Histopathologic specimens were confirmed as PSTT. No metastasis was detected. A total abdominal hysterectomy was performed.PSTT is a rare tumor. In contrast to other trophoblastic tumors, PSTT produces a small amount of ß-HCG and it is relatively insensitive to chemotherapy. Adjuvant chemotherapy is suggested to follow surgical treatment in the cases with metastasis.
Highlights
Placental site trophoblastic tumor (PSTT) is the rarest subtype of gestational trophoblastic neoplasia (GTN), characterized histologically by intermediate cytotrophoblasts [1]
200 cases of PSTT have been reported around the world [3]
A majority of GTNs are extremely sensitive to chemotherapy, PSTT is relatively resistant to it [5]
Summary
Placental site trophoblastic tumor (PSTT) is the rarest subtype of gestational trophoblastic neoplasia (GTN), characterized histologically by intermediate cytotrophoblasts [1]. It accounts for almost 1-2% of GTNs with an approximate incidence of 1/100.000 pregnancies. 200 cases of PSTT have been reported around the world [3]. It occurs in women of reproductive age and may occur after any pregnancy [4]. The purpose of this study was to present a 31-year-old case that presented to our clinic with complaints of irregular vaginal bleeding and was diagnosed with PSTT as a result of tests and examinations that were performed
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