Abstract
Abstract The use of methimazole for the treatment of hyperthyroidism in the first trimester of pregnancy has been linked to several congenital malformations. Most commonly reported is choanal atresia; however, other anomalies have been described including aplasia cutis, esophageal atresia, omphalomesenteric duct remnant, and omphalocele. A definitive phenotype of methimazole embryopathy has not been described. We report a case of a newborn with prenatal methimazole exposure who was found to have an H type tracheoesophageal (TE) fistula, vitelline fistula, ruptured omphalocele, as well as multiple duplication cysts of the stomach and small intestine.
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