Abstract

Adult intussusception represents 5% of all intussusceptions. Primary gastro-intestinal lymphoma comprises 1%-4% of all gastro- intestinal malignancies 90% of them are B-cell non-Hodgkin’s lymphoma (NHL). Most common NHL is diffuse large B-cell lymphoma accounts for 30-40%. Most common lymphoma causing intussusception is diffuse large B-cell lymphoma (DLBCL). We herein report a rare case of ileo-colic intussusception due to DLBCL in a 50- years-old male. Computed tomography showed ileo-colic intussusception with possibility of neoplastic etiology as a lead point. Hemicolectomy with ileo-colic anastomosis was done laparoscopically with post-operative chemotherapy. Subsequently, whole body positron emission tomography-computed tomography verified complete resolution of the malignancy. This study aims to present a rare case of ileo-colic intussusception due to non- Hodgkin’s B-cell lymphoma in a patient with unusual clinical course and highlight the importance of not only the timely surgical intervention but also the significance of strict adherence to follow up and chemotherapy will completely eradicate the malignancy.

Highlights

  • Abstract tion, an evident etiology is established in 70-90% of cases in adults and nearly 40% of them are caused by neoplasms

  • This study aims to present a rare case of ileo-colic intussusception due to nonm Hodgkin’s B-cell lymphoma in a patient o with unusual clinical course and highlight c the importance of the timely surgi

  • Adjuvant chemotherapy plays a pivotal role in the treatment of gastro-intestinal non-Hodgkin’s lymphoma (NHL) for the abolition of the tumor

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Summary

Introduction

An evident etiology is established in 70-90% of cases in adults and nearly 40% of them are caused by neoplasms. Most of the lead points in small intestine are benign neoplasms, and malignancy contributes only 30%.3. Primary gastro-intestinal lymphoma accounts for 1%-4% of all gastrointestinal malignancies. Most frequent primary sites are stomach (50%-60%) followed by small intestine (20-30%).[4] About 90% of primary gastro-intestinal lymphoma are B-cell non-Hodgkin’s lymphoma, followed by T-cell non-Hodgkin’s lymphoma and Hodgkin’s lymphoma. Most common part of small intestine affected by lymphoma is ileum followed by jejunum and

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