Abstract
Background: In India, Iron-deficiency anemia (IDA) among women Is a problem of major health significance. This study reviews the clinical trials on Ayurvedic management of IDA to generate evidence on their safety and efficacy. Objectives: The primary objective of the present study is systematic review of selected studies and published clinical data in view of safety and efficacy of Ayurvedic interventions in the management of IDA. Materials and methods: Randomized controlled trials (RCTs), quasi-RCTs (QRCT), controlled clinical trials (CCTs), and multiple-arm clinical trials that are of at least 3 weeks' duration will be included. Studies having patients fulfilling the diagnostic criteria based on the symptomatology of Pandu and IDA will be selected. Search strategy (for electronic search) Ayurveda OR Ayurvedic OR Ayurvedic treatment OR Pandu OR iron- deficiency anemia AND Mrit bhakshanajanya pandu as titles, abstracts, or keywords from online databases will be searched. Three investigators shall independently screen all citations and abstracts identified by a primary comprehensive search to sort out potentially eligible trials. Full articles of potentially eligible trials shall be obtained and independently evaluated for inclusion in the review based on the participants (inclusion criteria). Data extraction forms for individual study shall be prepared. Dissemination: The results of systematic review will be disseminated manually and electronically in peer-reviewed journals. The present systematic review may help the health authorities in framing health policies more effectively. Trial registration number: PROSPERO 2019 CDR42019131191 Dated 29/07/2019.
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