Abstract
The effects of the essential oil Nigella sativa was studied for its antihepatotoxic effects in rats against carbon tetrachloride (CCl4) which induced hepatocytic damage. The increased levels of serum enzymes (SGOT, SGPT and SAP) and bilirubin observed in rats treated with CCl4 were greatly reduced in the animals treated with N.sativa oil and CCl4. The decreased levels of proteins and albumin observed in rats after treatment with CCl4 were found to increase in rats treated with N. sativa oil and CCl4. These biochemical observations were supported by histopathological test of liver sections.
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